Real World Clinical Trials & Learning Health Systems Resources

Fact Sheets

Right-click to save, download and/or print these fact sheets. 

what is a learning health system? a fact sheet
Infographic outlining the difference between pragmatic clinical trials and real world clinical trials


Recommended Articles 

A framework for value-creating learning health systems
by Matthew Menear, Marc-André Blanchette, Olivier Demers-Payette and Denis Roy

  • Applying LHS to a Canadian context
  • 3 main components
    • Data collection & analysis
    • Acting on the data
    • Documenting results
  • Must be patient/person-centred

Embedding Research in the Learning Health System
by Robert J. Reid

  • Researchers have a solid skillset for improving and developing learning health systems
  • Integrating research into learning health systems just makes sense

The PRECIS-2 tool: Designing trials that are fit for purpose
Loudon K, Treweek S, Sullivan F, Donnan P, Thorpe K, Zwarenstein M

  • Details and context about how and why the tool was built
  • Use toolkit to implement